{"id":567,"date":"2024-03-13T13:58:49","date_gmt":"2024-03-13T12:58:49","guid":{"rendered":"https:\/\/knneuro.fuw.edu.pl\/?p=567"},"modified":"2025-06-03T14:47:14","modified_gmt":"2025-06-03T12:47:14","slug":"the-role-of-the-nasal-epithelium-in-the-generation-of-olfactory-bulb-rhythms-wyklad-wiktorii-podoleckiej","status":"publish","type":"post","link":"https:\/\/knneuro.fuw.edu.pl\/index.php\/2024\/03\/the-role-of-the-nasal-epithelium-in-the-generation-of-olfactory-bulb-rhythms-wyklad-wiktorii-podoleckiej\/","title":{"rendered":"The role of the nasal epithelium in the generation of olfactory bulb rhythms &#8211; wyk\u0142ad Wiktorii Podoleckiej"},"content":{"rendered":"\n<p>Serdecznie zapraszamy na pierwsze spotkanie Ko\u0142a Naukowego Neuroinformatyki w semestrze letnim. Tym razem b\u0119dziemy go\u015bci\u0107 prelegentk\u0119 <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-luminous-vivid-orange-color\">Wiktori\u0119 Podoleck\u0105<\/mark>, doktorantk\u0119 Pracowni Neuroinformatyki w Instytucie Biologii Do\u015bwiadczalnej im. M. Nenckiego PAN.<\/p>\n\n\n\n<p>Spotkanie odb\u0119dzie si\u0119 <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-luminous-vivid-orange-color\">w \u015brod\u0119 13.03.2024 o godzinie 17:00 w sali 1.01.<\/mark><\/p>\n\n\n\n<p><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-luminous-vivid-orange-color\">Po wyk\u0142adzie zapraszamy na spotkanie Ko\u0142a,<\/mark> gdzie b\u0119dziecie mieli okazj\u0119 dowiedzie\u0107 si\u0119 wi\u0119cej o naszej dzia\u0142alno\u015bci i do\u0142\u0105czy\u0107 w nasze szeregi.<\/p>\n\n\n\n<p class=\"has-text-align-center\"><strong><a rel=\"noreferrer noopener\" href=\"https:\/\/www.facebook.com\/events\/894156006049659?active_tab=about&amp;locale=pl_PL\" data-type=\"URL\" data-id=\"https:\/\/www.facebook.com\/events\/894156006049659?active_tab=about&amp;locale=pl_PL\" target=\"_blank\">Kliknij aby zobaczy\u0107\u00a0<mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-luminous-vivid-orange-color\">wydarzenie<\/mark>!<\/a><\/strong><\/p>\n\n\n\n<p><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-luminous-vivid-orange-color\">Abstrakt wyk\u0142adu:<\/mark><br>Changes in olfaction are emerging as early warning signs of several major neurological diseases. Neurological diseases are also associated with aberrant brain rhythms. Olfactory sensory neurons (OSN) deliver input from the nasal epithelium (NE) to the olfactory bulb (OB) and are key drivers of rhythmicity.<br>Here, we examine the role of sensory input arising from the NE in the generation of electrophysiological rhythms in the OB. Rats were implanted with electrodes in the OB, PFC and VS. Post-surgery gadolinium\/saline was infused bilaterally to both nares. Ketamine infusions were done every 4 days. Behavioral tests to test anosmia were done every 2 days. Olfactory marker protein (OMP) immunohistochemistry was used to stain for OSN at different time points. Analyses of LFPs, during waking, revealed reduced amplitude of HFO (130-180 Hz) in gadolinium-infused rats compared to saline-infused rats. This effect lasted up to 10 days. Behavioural tests have shown that anosmia lasted around 10 days.<br>Immunohistochemical analyses revealed gadolinium infusion was associated with weaker OMP staining in the NE. Given that the OB can orchestrate brain-wide rhythms, we speculate that early deficits in olfactory function may contribute, at least in part, to changes in brain rhythms reported in neuropsychiatric diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Serdecznie zapraszamy na pierwsze spotkanie Ko\u0142a Naukowego Neuroinformatyki w semestrze letnim. Tym razem b\u0119dziemy go\u015bci\u0107 prelegentk\u0119 Wiktori\u0119 Podoleck\u0105, doktorantk\u0119 Pracowni Neuroinformatyki w Instytucie Biologii Do\u015bwiadczalnej im. M. Nenckiego PAN. Spotkanie odb\u0119dzie si\u0119 w \u015brod\u0119 13.03.2024 o godzinie 17:00 w sali 1.01. Po wyk\u0142adzie zapraszamy na spotkanie Ko\u0142a, gdzie b\u0119dziecie mieli okazj\u0119 dowiedzie\u0107 si\u0119 wi\u0119cej o &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/knneuro.fuw.edu.pl\/index.php\/2024\/03\/the-role-of-the-nasal-epithelium-in-the-generation-of-olfactory-bulb-rhythms-wyklad-wiktorii-podoleckiej\/\" class=\"more-link\">Czytaj dalej<span class=\"screen-reader-text\"> \u201eThe role of the nasal epithelium in the generation of olfactory bulb rhythms &#8211; wyk\u0142ad Wiktorii Podoleckiej\u201d<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":570,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-567","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-wyklad"],"_links":{"self":[{"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/posts\/567","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/comments?post=567"}],"version-history":[{"count":1,"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/posts\/567\/revisions"}],"predecessor-version":[{"id":571,"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/posts\/567\/revisions\/571"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/media\/570"}],"wp:attachment":[{"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/media?parent=567"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/categories?post=567"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/knneuro.fuw.edu.pl\/index.php\/wp-json\/wp\/v2\/tags?post=567"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}